01
Cellular Energy
Cells require a constant supply of energy to power everything from movement to mental performance.
The Science of Eternal
Rooted in Nature.
Refined by Science.
Healthy aging begins at the cellular level. Eternal NAD+ combines three purposeful activesβNAD+, Quercetin, and Resveratrolβto support the cellular processes behind energy, antioxidant defense, vitality, and healthy aging.*
5.0 out of 5.0 Β· 317 reviews
Cellular Energy
NAD+ Β· 500 mg
Antioxidant
Quercetin Β· 250 mg
Healthy Aging
Resveratrol Β· 150 mg
- 3 Purposeful Actives
- Transparent Formula
- Designed for Daily Support
Start Beneath the Surface
Healthy Aging Starts With Your Cells
Every moment of your life depends on trillions of cells producing energy, responding to stress, repairing themselves, and communicating with one another.
As we age, many of these cellular processes can become less efficient. That is why modern healthy-aging research increasingly focuses on supporting the biological systems that help cells function optimally over time.[1]
Eternal NAD+ was built around that philosophy: support the foundation first.
02
Oxidative Balance
Everyday metabolism creates oxidative stress. Antioxidant compounds help support the body's natural defenses against it.*
03
Cellular Maintenance
Healthy cells rely on complex pathways involved in metabolism, signaling, and cellular maintenance.
04
Long-Term Vitality
Supporting cellular wellness is one piece of maintaining energy, resilience, and vitality throughout life.*
The mitochondrion
Where much of the cell's energy metabolism takes place
The Foundation
What Is NAD+?
nicotinamide adenine dinucleotide
NAD+, short for nicotinamide adenine dinucleotide, is a naturally occurring coenzyme found throughout the body.[1]
It plays an essential role in cellular metabolism and the chemical reactions cells use to produce energy.[1,2]
NAD+ also participates in pathways associated with cellular signaling, metabolic regulation, DNA maintenance, and other fundamental biological processes that researchers continue to study in connection with healthy aging.[1,3,5]
Think of NAD+ as part of the cellular machinery that helps turn nutrients into usable energy.
Why NAD+ Has Become a Focus of Healthy-Aging Research
Scientific research has found that NAD+ availability can change with age and has generated significant interest in understanding its relationship with metabolism, cellular function, and healthy aging.[3,4,6]
What we know
NAD+ is essential to cellular metabolism, and human tissue studies have reported age-associated changes in NAD+ metabolism.
Still being studied
Much of the research linking NAD+ to aging comes from cell and animal models. How those findings apply to people is still being established.
Three Purposeful Actives
Designed to Support Aging From Multiple Angles
Instead of overcrowding the label with dozens of ingredients, Eternal NAD+ focuses on three complementary compounds selected to support cellular energy, antioxidant defense, and healthy-aging wellness.*
01
Cellular Energy
NAD+
500 mgNicotinamide adenine dinucleotide
NAD+ is a naturally occurring coenzyme involved in essential metabolic reactions throughout the body.[1]
It plays a central role in cellular energy metabolism and also serves as a substrate for enzymes involved in important cellular processes.[2,5]
With 500 mg per serving, NAD+ forms the foundation of the Eternal formula.*
02
Antioxidant Defense
Quercetin
250 mgSophora japonica flower bud
Quercetin is a naturally occurring plant flavonoid found in many fruits and vegetables.[7]
It has been extensively studied for its antioxidant properties and its interaction with cellular pathways associated with oxidative stress and overall cellular wellness.*[7,8]
Our Quercetin is derived from Sophora japonica flower buds.
03
Healthy Aging
Resveratrol
150 mgJapanese Knotweed Extract β’ 98% Resveratrol
Resveratrol is a naturally occurring polyphenol found in several plants and has become one of the most widely researched compounds in the healthy-aging space.[10]
Research has explored its antioxidant activity and interaction with pathways involved in cellular stress response and metabolic health.*[10,11,12]
Eternal uses Japanese Knotweed Extract standardized to 98% Resveratrol.
A Complementary Approach
More Than NAD+ Alone
NAD+
Supports cellular energy and metabolic processes.*
Quercetin
Provides plant-based antioxidant support.*
Resveratrol
Provides complementary antioxidant and healthy-aging support.*
One Simple Daily Ritual
Eternal NAD+ brings these three ingredients together in a focused formula designed to support cellular wellness from multiple anglesβwithout an overloaded ingredient list.*
- Complementary
- Purposeful
- Thoughtfully Paired
The research referenced on this page concerns the individual ingredients, not the finished Eternal NAD+ formula.
Why It Matters
Science Beneath the Surface. Vitality You Can Build On.
Energy
Power the moments that matter.
Supporting cellular energy can help provide the biological foundation behind the active, full life you want to keep living.*
Clarity
Stay present for what matters most.
The brain is highly energy-dependent. Supporting cellular wellness is part of supporting overall cognitive health and mental performance as you age.*
Resilience
Support your cells against everyday oxidative stress.
Quercetin and Resveratrol provide antioxidant support designed to complement the body's natural cellular defenses.*
Healthy Aging
Invest in how you want to feel tomorrow.
Healthy aging is not one pathway, ingredient, or quick fix. It is the result of consistently supporting the systems your body relies on throughout life.*
Because aging well isn't about chasing youth. It's about protecting the energy, confidence, and vitality that make you feel like yourself.
The Science, Visualized
From Cellular Support to Everyday Wellness
-
01
Nutrition
-
02
Cellular Metabolism
-
03
Energy Production
-
04
Antioxidant Defense
-
05
Cellular Wellness
-
06
Everyday Vitality
The human body is extraordinarily complex. No supplement controls the aging process. Eternal NAD+ is designed to support key aspects of cellular wellness as one part of a healthy lifestyle that includes nutritious food, movement, quality sleep, hydration, and preventive healthcare.*
- Nutritious food
- Movement
- Quality sleep
- Hydration
- Preventive healthcare
Peer-Reviewed Research
Built Around Biology That Scientists Are Actively Studying
- Foundational biology
- Preclinical (cell & animal)
- Human research
NAD+ & Cellular Metabolism
NAD+ is an essential coenzyme involved in cellular metabolism, redox reactions, and energy production. Research has also examined NAD+-dependent pathways in relation to cellular maintenance and aging biology.
Evidence note: NAD+'s role in metabolism is foundational biology. Much of the research on NAD+ and aging comes from cell and animal models; human research is ongoing.
- Lautrup et al. β Roles of NAD+ in Health and Aging. Cold Spring Harb Perspect Med, 2024. PMID 37848251
- Covarrubias et al. β NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol, 2021. PMID 33353981
- Verdin β NAD+ in aging, metabolism, and neurodegeneration. Science, 2015. PMID 26785480
Quercetin & Antioxidant Research
Quercetin is a plant-derived flavonoid studied extensively for antioxidant activity, oxidative stress, inflammatory pathways, and other aspects of cellular health.
Evidence note: Findings differ by population, formulation, dose, and endpointβand many laboratory findings have not been confirmed in human trials.
- Boots et al. β Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol, 2008. PMID 18417116
- Li et al. β Quercetin, Inflammation and Immunity. Nutrients, 2016. PMID 26999194
- Andres et al. β Safety Aspects of the Use of Quercetin as a Dietary Supplement. Mol Nutr Food Res, 2018. PMID 29127724
Resveratrol & Cellular Defense
Resveratrol is a plant polyphenol researched for its antioxidant activity and its interactions with cellular signaling and stress-response pathways.
Evidence note: Human trial outcomes vary, and mechanistic findings from cell and animal research do not necessarily translate into meaningful clinical outcomes.
- Systematic review & meta-analysis of randomized clinical trials examining resveratrol and oxidative stress. PMID 31738139
- Berman et al. β The therapeutic potential of resveratrol: a review of clinical trials. NPJ Precis Oncol, 2017. PMID 28989978
- Baur & Sinclair β Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov, 2006. PMID 16732220
Our Approach
Science Should Build Trust, Not Hype.
Healthy-aging science is evolving quickly. We believe you deserve to know the difference between what biology tells us, what early research suggests, and what human clinical research has actually demonstrated.
That's why Eternal Nutrients focuses on purposeful ingredients, transparent amounts, responsible claims, and continued attention to emerging research.
Transparent Amounts
No mystery around what you're taking.
Purposeful Formulation
Every active has a reason for being here.
Evidence-Informed
Formulated around compounds actively studied in cellular and healthy-aging research.
No Miracle Claims
Healthy aging is a long-term investment, not an overnight transformation.
Formula at a Glance
Simple by Design
2 Capsules Daily60 capsules Β· 30 servings
Three purposeful actives. One simple daily ritual.
Shop Eternal NAD+Supplement Facts
Serving size: 2 capsules Β· Servings per container: 30
Per servingAmount
- NAD+Nicotinamide adenine dinucleotide
- 500 mg
- Quercetin Dihydrate ExtractDerived from Sophora japonica flower bud
- 250 mg
- Japanese Knotweed ExtractStandardized to 98% Resveratrol
- 150 mg
Daily Value not established. Other ingredients: HPMC (vegetable capsule), microcrystalline cellulose, brown rice flour, olive oil, silicon dioxide, magnesium stearate.
Science FAQ
Your Questions, Answered Honestly
Clear answers about what the science saysβand what it doesn't.
What exactly does NAD+ do?
NAD+ is a coenzyme required for numerous cellular reactions, including reactions involved in turning nutrients into usable cellular energy. It is also used by several families of enzymes involved in cellular signaling and maintenance.[1,2]
Does NAD+ decline with age?
Research has reported age-associated changes in NAD+ metabolism and NAD+ availability, although the magnitude and consistency of those changes in humans can vary between tissues and studies.[3,4]
Why include antioxidants with NAD+?
Quercetin and Resveratrol provide complementary antioxidant support and have each been studied for their interactions with cellular stress-response pathways.*[7,10]
Does Eternal NAD+ reverse aging?
No supplement can reverse the aging process. Eternal NAD+ is designed to support cellular energy, antioxidant defense, wellness, and healthy aging as part of a consistent healthy lifestyle.*
Has this exact formula been clinically studied?
The research referenced on this page concerns the individual ingredientsβNAD+, Quercetin, and Resveratrolβnot the finished Eternal NAD+ formula. Each ingredient is supported by a different level and type of scientific research, from foundational biology to human clinical trials. We developed the formula based on the biological roles of these compounds and the research surrounding them, and we're careful not to claim more than that evidence supports.
How should I take Eternal NAD+?
Take 2 capsules daily with water as part of a consistent wellness routine. If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare provider before use.
Your Daily Longevity Ritual
Your Best Years Are Still Ahead.
Support the cellular foundation behind energy, vitality, and healthy aging with three purposeful ingredients in one simple daily ritual.*
Free Shipping 30-Day Satisfaction Guarantee
Shop Eternal NAD+ β full detailsAge on Your Terms.
Scientific References12 peer-reviewed sources cited on this page
- [1]Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology. 2021;22(2):119β141. doi:10.1038/s41580-020-00313-x. PMID 33353981
- [2]Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015;350(6265):1208β1213. doi:10.1126/science.aac4854. PMID 26785480
- [3]Lautrup S, Hou Y, Fang EF, Bohr VA. Roles of NAD+ in Health and Aging. Cold Spring Harbor Perspectives in Medicine. 2024;14(1):a041193. doi:10.1101/cshperspect.a041193. PMID 37848251
- [4]Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin GJ. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One. 2012;7(7):e42357. doi:10.1371/journal.pone.0042357. PMID 22848760
- [5]Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends in Cell Biology. 2014;24(8):464β471. doi:10.1016/j.tcb.2014.04.002. PMID 24786309
- [6]Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metabolism. 2018;27(3):529β547. doi:10.1016/j.cmet.2018.02.011. PMID 29514064
- [7]Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. European Journal of Pharmacology. 2008;585(2β3):325β337. doi:10.1016/j.ejphar.2008.03.008. PMID 18417116
- [8]Li Y, Yao J, Han C, et al. Quercetin, Inflammation and Immunity. Nutrients. 2016;8(3):167. doi:10.3390/nu8030167. PMID 26999194
- [9]Andres S, Pevny S, Ziegenhagen R, et al. Safety Aspects of the Use of Quercetin as a Dietary Supplement. Molecular Nutrition & Food Research. 2018;62(1). doi:10.1002/mnfr.201700447. PMID 29127724
- [10]Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nature Reviews Drug Discovery. 2006;5(6):493β506. doi:10.1038/nrd2060. PMID 16732220
- [11]Berman AY, Motechin RA, Wiesenfeld MY, Holz MK. The therapeutic potential of resveratrol: a review of clinical trials. NPJ Precision Oncology. 2017;1:35. doi:10.1038/s41698-017-0038-6. PMID 28989978
- [12]Systematic review and meta-analysis of randomized clinical trials examining the effects of resveratrol on oxidative stress markers. PMID 31738139
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.